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Patients can also show the following: п‚· Psychomotor retardation п‚· Flattening or loss of reactivity within the affected person’s have an effect on (ie, emotional expression) п‚· Psychomotor agitation or restlessness Major depressive dysfunction Among the criteria for a significant depressive disorder, no less than 5 of the following symptoms need to have been present during the identical 2-week interval (and no less than 1 of the symptoms have to be diminished curiosity/pleasure or depressed temper): п‚· Depressed temper: For children and adolescents, this may also be an irritable temper п‚· Diminished curiosity or loss of pleasure in almost all activities (anhedonia) п‚· Significant weight change or appetite disturbance: For youngsters, this can be failure to achieve anticipated weight acquire п‚· Sleep disturbance (insomnia or hypersomnia) п‚· Psychomotor agitation or retardation п‚· Fatigue or loss of power п‚· Feelings of worthlessness п‚· Diminished ability to assume or concentrate; indecisiveness п‚· Recurrent thoughts of demise, recurrent suicidal ideation with no particular plan, or a suicide try or specific plan for committing suicide 275 Self-report screening devices for despair embrace the next: Management In all affected person populations, the mixture of treatment and psychotherapy usually provides. 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