Schrooten 1993 (Continued) sympathomimetics, anticholinergics Duration of symptoms earlier than inclusion: 24 hours or much less Interventions Astemizole 10 mg + pseudoephedrine 240 mg (managed launch) 1 x/day Control: placebo Duration of treatment: 7 days Outcomes Symptom severity rating (4-level scale): nasal discharge, nasal obstruction, sneezing, cough, basic discomfort) Weight of nasal secretions: weight of used paper tissues General impression Adverse effect Notes Funding supply: not reported but ethics approval from Janssen Research Foundation Risk of bias Bias AuthorsпїЅ judgement Support for judgement Random sequence era (choice Low risk пїЅThe trial was designed as a double-blind bias) comparability in parallel teams between astemizole-D and placebo. 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